Subject. This article deals with the issues related to the introduction of simulation technologies in business processes based on the data bulk processing. Objectives. The article intends to propose the use of simulation modeling in public administration, namely at the level of interregional cooperation in certain federal districts. Methods. For the study, we used a proposed model of foresight of the federal district's innovation system evolution, based on the use of a multiobjective genetic algorithm. Results. The article offers specific ways, approaches and solutions to enhance the synergies of the federal district.
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