Subject. This article deals with the issues of epidemiological protection of the population. Objectives. The article aims to assess the impact of opportunities to ensure isolation of the population on the spread of coronavirus infection and the demographic situation in the Amur Oblast. Methods. For the study, we used a statistical analysis. Results. The article defines the groups of municipalities of the Amur Oblast, which differ in the extent of the population mortality increase during the COVID-19 pandemic. Conclusions and Relevance. There is a need for a differentiated approach to ensuring epidemiological protection of the population. The findings could help improve quarantine measures to protect the public and choose tools to organize social distancing.
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