Subject. This article deals with the issues related to the economic efficiency and well-being of the population. Objectives. The article aims to analyze the impact of the economic activity of people in the existing institutional environment on the socio-economic development of megaregions. Methods. The article uses indices that determine the public business activity and the effectiveness of the State's economic policy. Results. The article presents an original methodology for assessing the socio-economic dynamics of federal districts between 2004 and 2018. The article points out the decline in business activity of the population and the increasing dependence of welfare on social assistance by the State. Conclusions. The article concludes that it is necessary to adjust the public policy to encourage the business activity of people.
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