Importance This research substantially summarizes a number of studies into the University - Science City - Region triad and learning environment in Russia at various hierarchical levels. Objectives We make the first attempt of comparing the University - Science City - Region triad with the concurrent Western research, i.e. The triple helix of University - Industry - Government relations by H. Etzkowitz, Professor of Stanford University. Methods We propose an analytical approach the paradigm of which constitutes a concept that is based on a number of principles, and methodology comprised of a number of methods and techniques. The fundamental methodological principle is represented with the principle of advanced function of education. As prescribed by this principle, the development of education should outperform the pace of economic development so that education would act as the driving force of economic development. The research components rely upon the methods of numerical and non-numerical statistics, including parametric/non-parametric correlation and regression analysis, expert methods, theory of fuzzy sets, and data of the official statistical websites of Russia. Results We present some generalized results of the research into methodology and instrumental bases of evaluating the effect of education on the development of socio-economic systems at various hierarchal level that strive for the 6th economic mode, i.e. economy of knowledge. The proposed instruments are of recurring nature. It is important for evaluating the current position of objects under study, adjusting tactical decisions to achieve and/or realign development strategies. It helps address issues of the national economy and regional development. Conclusions and Relevance We demonstrate that such researches gain special political and ideological relevance. They help understand the role of Russia in today's world. We conclude that the combined approach of the triple helix and University - Science City - Region triad may be regarded as a new area of research into the learning environment in the social and economic milieu, being a complex system, which, if sustainably developed, will lead to the new economic mode of knowledge-based economy.
Keywords: Triple Helix model, knowledge-based economy, principle, advance function, education, socio-economic development, methodology, instrumental methods, integrated indicator, field theory, human capital
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