Subject. This article discusses instruments, methods, and mechanisms for implementing import substitution policy in the Russian national innovation system. Objectives. The article aims to present a comparative analysis and assessment of the current implementation state of import substitution policies in high-tech industry sectors. Methods. For the study, we used the general scientific methods: description, system analysis, and comparative characterization. Results. The article reveals a significant advantage and superiority of high-tech and medium-tech high-level productions over the medium-sized industries. Conclusions. It is necessary to transfer technologies from leading industries in the international market to sectors of catching-up technological development. The mechanism of such transfer must undergo fine-tuning and adaptation to ensure the effective development of the national economy.
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