Subject. Features of modelling and assessing investment risks in domestic medical electronics under priority-driven import substitution development. Objectives. To identify key factors affecting the financial stability of investment projects in the sector and to develop approaches for minimizing specific risks. Methods. Economic-mathematical modelling was used. Results. It has been established that integrating import substitution factors into investment analysis helps reduce cash flow volatility and increases the likelihood of reaching the break-even point. The developed scenario forecasting methodology shows that accounting for import substitution specifics not only reduces vulnerability to external shocks but also helps identify new opportunities for sustainable development of medical electronics. An economic-mathematical model has been proposed that incorporates import substitution into investment risk analysis. Scope of Application. The findings can serve as a practical guide for investors, developers, and innovators in domestic medical electronics amid economic uncertainty. The presented methods are suitable for application in related high-tech sectors. Conclusions. Accounting for import substitution factors reduces external risks and opens up new opportunities for the sector.
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